Speaker
Description
In this talk, we study a phase-field model for curvature-driven pattern formation in biomembranes. The model is derived as a gradient flow of an energy functional that approximates the two-phase Canham--Helfrich energy. This leads to a Cahn--Hilliard-type equation with cross diffusion for the relative chemical concentration of one lipid phase, coupled to a fourth-order reaction-diffusion equation describing the height profile of the membrane.
We first discuss the existence of weak solutions for the case of regular double-well potentials, using a minimizing movement scheme to construct approximate solutions. The analysis is then extended to singular potentials, e.g., the Flory--Huggins potential, by approximating them with a Moreau--Yosida regularization.
For both cases, we establish higher regularity, continuous dependence on the initial data, and consequently the uniqueness of weak solutions.
Finally, we propose a well-posed finite element discretization of the model and present numerical experiments illustrating the effect of different physical parameters on the resulting membrane patterns. Depending on the parameter regime, we observe purely striped, dotted, or snake-like structures.
(This talk is based on joint work with Patrik Knopf (UR, KIT) and Anastasija Pešić (WIAS).)